PLA2G5 and STC2

Data Source:
BioGRID (affinity chromatography technology)

		PLA2G5	STC2
Description		phospholipase A2 group V	stanniocalcin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Golgi Apparatus Plasma Membrane Early Phagosome Phagolysosome Recycling Endosome	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Fatty Acid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Macrophage Derived Foam Cell Differentiation Leukotriene Biosynthetic Process Low-density Lipoprotein Particle Remodeling Phosphatidylcholine Catabolic Process Cardiolipin Acyl-chain Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Arachidonic Acid Secretion Positive Regulation Of Phagocytosis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Phagosome-lysosome Fusion Positive Regulation Of Opsonization Positive Regulation Of Antifungal Innate Immune Response Positive Regulation Of Phagosome Maturation	Cellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Gene Expression Response To Vitamin D Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Decidualization Regulation Of Hormone Biosynthetic Process Cellular Response To Hypoxia
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Urate levels in overweight individuals ( 25811787)
Interacting Genes		1 interacting genes: PLA2G4A	11 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 EIF2B3 PEBP1 POLR2C POLR3F PPP1R8 PTN
Entrez ID		5322	8614
HPRD ID		03117	04717
Ensembl ID		ENSG00000127472	ENSG00000113739
Uniprot IDs		P39877	O76061 Q6FHC9
PDB IDs		2GHN
Enriched GO Terms of Interacting Partners?
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