SMG1

Description		SMG1 nonsense mediated mRNA decay associated PI3K related kinase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol TORC1 Complex TORC2 Complex
	Molecular Function	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Telomeric DNA Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Repair MRNA Export From Nucleus Negative Regulation Of Macroautophagy Peptidyl-serine Phosphorylation Regulation Of Telomere Maintenance TORC1 Signaling Protein Autophosphorylation Phosphatidylinositol Phosphorylation Regulation Of Response To DNA Damage Stimulus
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Health literacy ( 31250787) Heel bone mineral density ( 30598549) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: ELOB
Interacting Genes		9 interacting genes: CDH5 PRKCI SMAD9 SMG5 SMG8 SNAPIN UPF1 UPF2 UPF3A
Entrez ID		23049
HPRD ID		06123
Ensembl ID		ENSG00000157106
Uniprot IDs		Q96Q15
PDB IDs		6L53 6L54 6SYT 6Z3R
Enriched GO Terms of Interacting Partners?
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