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ATF6
Description
activating transcription factor 6
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Chromatin
Nucleus
Nuclear Envelope
Nucleoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
CAMP Response Element Binding
Identical Protein Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Eye Development
Regulation Of Transcription By RNA Polymerase II
Protein Folding
Signal Transduction
Visual Perception
Positive Regulation Of Autophagy
Endoplasmic Reticulum Unfolded Protein Response
ATF6-mediated Unfolded Protein Response
Positive Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of ATF6-mediated Unfolded Protein Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
ATF6 (ATF6-alpha) activates chaperones
ATF6 (ATF6-alpha) activates chaperone genes
ATF6 (ATF6-alpha) activates chaperone genes
Drugs
Pseudoephedrine
Diseases
GWAS
Chronic bronchitis in chronic obstructive pulmonary disease (
25241909
)
Parkinson's disease (age of onset) (
19772629
)
Systemic sclerosis (
30247649
)
Interacting Genes
15 interacting genes:
APP
ATF6B
BPGM
CREB1
CREB3L3
DAPK1
DDC
GTF2I
NFYA
NFYC
NNMT
SRF
TNFRSF1A
XBP1
YY1
Entrez ID
22926
HPRD ID
16118
Ensembl ID
ENSG00000118217
Uniprot IDs
A8K383
P18850
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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