AGAP2

Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Membrane Extracellular Exosome Flemming Body
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Protein Kinase Binding Protein Kinase Activator Activity Phosphatidylinositol 3-kinase Regulator Activity Metal Ion Binding
	Biological Process	Protein Transport Endosomal Transport Actin Cytoskeleton Organization Activation Of Protein Kinase Activity Negative Regulation Of Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity
Pathways		Netrin-1 signaling
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Multiple sclerosis ( 21833088)
Novel Interacting Genes		1 novel interacting genes: TBK1
Interacting Genes		13 interacting genes: AKT1 ARF1 CDC42 EPB41L1 GRIP1 HOMER1 HOMER2 NF2 PIK3R1 PLCG1 RAC1 RAC2 RHOA
Entrez ID		116986
HPRD ID		05687
Ensembl ID		ENSG00000135439
Uniprot IDs		A0A024RB55 F8VVT9 Q99490
PDB IDs		2BMJ 2IWR 2RLO
Enriched GO Terms of Interacting Partners?
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