PADI2

Description		peptidyl arginine deiminase 2
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Transcriptionally Active Chromatin Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein-arginine Deiminase Activity Calcium Ion Binding Estrogen Receptor Binding Protein Homodimerization Activity
	Biological Process	Chromatin Organization Regulation Of Chromatin Disassembly Protein Citrullination Substantia Nigra Development Intracellular Estrogen Receptor Signaling Pathway Histone H3-R26 Citrullination Histone Citrullination Neutrophil Degranulation Chromatin-mediated Maintenance Of Transcription Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Lymphocyte Chemotaxis Cellular Response To Leukemia Inhibitory Factor
Pathways		Chromatin modifying enzymes Neutrophil degranulation
Drugs		Citrulline
Diseases
GWAS		Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hemoglobin ( 32888494) Prudent dietary pattern ( 28644415) Rheumatoid arthritis ( 30423114) Visceral fat ( 30942860)
Novel Interacting Genes		2 novel interacting genes: EMC1 PADI4
Interacting Genes
Entrez ID		11240
HPRD ID		06396
Ensembl ID		ENSG00000117115
Uniprot IDs		Q9Y2J8
PDB IDs		4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N
Enriched GO Terms of Interacting Partners?
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