PADI2 and EMC1

Data Source:
BioGRID (affinity chromatography technology)

		PADI2	EMC1
Description		peptidyl arginine deiminase 2	ER membrane protein complex subunit 1
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Transcriptionally Active Chromatin Azurophil Granule Lumen Extracellular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex
	Molecular Function	Protein-arginine Deiminase Activity Calcium Ion Binding Estrogen Receptor Binding Protein Homodimerization Activity	Membrane Insertase Activity
	Biological Process	Chromatin Organization Regulation Of Chromatin Disassembly Protein Citrullination Substantia Nigra Development Intracellular Estrogen Receptor Signaling Pathway Histone H3-R26 Citrullination Histone Citrullination Neutrophil Degranulation Chromatin-mediated Maintenance Of Transcription Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Lymphocyte Chemotaxis Cellular Response To Leukemia Inhibitory Factor	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Chromatin modifying enzymes Neutrophil degranulation
Drugs		Citrulline
Diseases
GWAS		Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hemoglobin ( 32888494) Prudent dietary pattern ( 28644415) Rheumatoid arthritis ( 30423114) Visceral fat ( 30942860)
Interacting Genes
Entrez ID		11240	23065
HPRD ID		06396	08306
Ensembl ID		ENSG00000117115	ENSG00000127463
Uniprot IDs		Q9Y2J8	Q8N766
PDB IDs		4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N	6WW7 6Z3W
Enriched GO Terms of Interacting Partners?
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