MAP3K2

Description		mitogen-activated protein kinase kinase kinase 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Activation Of MAPKK Activity Activation Of MAPK Activity Protein Phosphorylation Activation Of JUN Kinase Activity Positive Regulation Of Transcription, DNA-templated Cellular Response To Mechanical Stimulus
Pathways
Drugs		Bosutinib Fostamatinib
Diseases
GWAS		Protein C levels ( 28082259)
Novel Interacting Genes		1 novel interacting genes: NGLY1
Interacting Genes		24 interacting genes: BIRC2 CTNNB1 IKBKG MAP2K3 MAP2K4 MAP2K5 MAP2K7 MAP3K5 MAPK8 NEDD4 NEDD4L NFKBIA PIBF1 PKN2 SH2D2A SMURF1 STAMBP STUB1 USP2 WNK1 XIAP YWHAE YWHAG YWHAZ
Entrez ID		10746
HPRD ID		10068
Ensembl ID		ENSG00000169967
Uniprot IDs		A0A024RAH0 Q9Y2U5
PDB IDs		2CU1 2NPT 5EX0 5HQ8
Enriched GO Terms of Interacting Partners?
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