Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

SH2B2

Description SH2B adaptor protein 2
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
Molecular Function
  • Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
  • Protein Binding
  • Signaling Adaptor Activity
  • SH2 Domain Binding
Biological Process
  • Blood Coagulation
  • Insulin Receptor Signaling Pathway
  • Intracellular Signal Transduction
  • Antigen Receptor-mediated Signaling Pathway
  • B Cell Receptor Signaling Pathway
Pathways
  • Regulation of KIT signaling
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Type 2 diabetes ( 31049640)
Novel Interacting Genes 1 novel interacting genes: JADE2
Interacting Genes 42 interacting genes: AKT1 ASB6 BTK CBL CLK1 CLK3 DUSP13 EGFR EPOR ERBB2 ERBB4 FAM124B FAM90A1 FYN GRB2 HCK IL36RN INSR JAK1 JAK2 JAK3 KIT LMO3 LYN MAGEH1 MCRS1 MET MTDH NTRK1 NTRK2 PDLIM7 PLEKHA3 RAB6B SH2B1 SHC1 SORBS1 SYK TLE5 TLNRD1 USP2 ZNF414 ZNF417
Entrez ID 10603
HPRD ID 16097
Ensembl ID ENSG00000160999
Uniprot IDs O14492
PDB IDs 1Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025