AATK and STYX

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		AATK	STYX
Description		apoptosis associated tyrosine kinase	serine/threonine/tyrosine interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Pseudophosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity F-box Domain Binding
	Biological Process	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation	Protein Dephosphorylation Negative Regulation Of Protein Binding Negative Regulation Of Catalytic Activity MAPK Export From Nucleus Negative Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Prostate cancer ( 23535732)
Interacting Genes		43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2	24 interacting genes: AATK CARHSP1 EGFR EPHA2 EPHA3 EPHA7 EPHB6 ERBB2 ERBB3 ERBB4 FBXO7 FBXW7 IGF1R INSR INSRR KDR KIT LMTK2 MAPK1 MUSK PTK7 ROR1 ROR2 TEK
Entrez ID		9625	6815
HPRD ID		05591	10258
Ensembl ID		ENSG00000181409	ENSG00000198252
Uniprot IDs		H7C175 Q6ZMQ8	A0A024R641 Q8WUJ0
PDB IDs			2R0B
Enriched GO Terms of Interacting Partners?
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