AATK and PTPN18

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		AATK	PTPN18
Description		apoptosis associated tyrosine kinase	protein tyrosine phosphatase non-receptor type 18
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation	Blastocyst Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of ERBB Signaling Pathway
Pathways			Downregulation of ERBB2 signaling Interleukin-37 signaling
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2	12 interacting genes: AATK ABL1 ARHGAP5 CDK2 CSK EGFR ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC
Entrez ID		9625	26469
HPRD ID		05591	05961
Ensembl ID		ENSG00000181409	ENSG00000072135
Uniprot IDs		H7C175 Q6ZMQ8	Q99952
PDB IDs			2OC3 4GFU 4GFV 4NND
Enriched GO Terms of Interacting Partners?
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