AATK and PTPN7

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		AATK	PTPN7
Description		apoptosis associated tyrosine kinase	protein tyrosine phosphatase non-receptor type 7
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation	MAPK Cascade Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways			Negative regulation of MAPK pathway Interleukin-37 signaling
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Basophil percentage of white cells ( 32888494) Breast cancer ( 23535733) Mean spheric corpuscular volume ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2	17 interacting genes: AATK APP CCDC57 EGFR EPHA2 ERBB3 ERBB4 GMCL1 IGF1R MAPK1 MAPK14 MAPK3 PPP1CA PRKACA PTK7 ROR2 SIRPA
Entrez ID		9625	5778
HPRD ID		05591	01480
Ensembl ID		ENSG00000181409	ENSG00000143851
Uniprot IDs		H7C175 Q6ZMQ8	A0A024R9A7 B4DZD9 P35236
PDB IDs			1ZC0 2A3K 2GP0 2GPH 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4S 3O4T 3O4U
Enriched GO Terms of Interacting Partners?
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