PER2 and PER3

Number of citations of the paper that reports this interaction (PubMedID 10837028)
64

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PER2	PER3
Description		period circadian regulator 2	period circadian regulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding Transcription Corepressor Binding Transcription Coactivator Activity Protein Binding	Transcription Cis-regulatory Region Binding Transcription Corepressor Binding Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Fatty Acid Metabolic Process Circadian Rhythm Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Transcription Regulatory Region DNA Binding	Negative Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Regulation Of Circadian Sleep/wake Cycle, Sleep Protein Stabilization
Pathways		Circadian Clock
Drugs
Diseases
GWAS		Chronotype ( 26955885 30696823 27494321) Morning vs. evening chronotype ( 26955885 26835600 27494321)	Chronotype ( 30696823) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Ulcerative colitis ( 28067908)
Interacting Genes		22 interacting genes: BHLHE41 BTRC CLOCK CRY1 CRY2 CSNK1D CSNK1E CSNK2B DELEC1 ELOA LENG8 LMO4 MDM2 MLH1 PER1 PER3 RORC TIMELESS TP53 TPT1 TPTEP2-CSNK1E UBL4A	9 interacting genes: ARNTL CLOCK CRY1 CRY2 CSNK1D CSNK1E PER1 PER2 SP1
Entrez ID		8864	8863
HPRD ID		04575	09138
Ensembl ID		ENSG00000132326	ENSG00000049246
Uniprot IDs		O15055	A0A087WV69 A2I2N5 P56645
PDB IDs		6OF7
Enriched GO Terms of Interacting Partners?
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