PIN4 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PIN4	ASCC2
Description		peptidylprolyl cis/trans isomerase, NIMA-interacting 4	activating signal cointegrator 1 complex subunit 2
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Mitochondrial Matrix Spindle	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization RRNA Processing	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways			ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Rosacea symptom severity ( 29771307)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		19 interacting genes: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAD1L1 MAGEA11 PNMA1 SPTAN1 ZBTB9	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		5303	84164
HPRD ID		02219	16515
Ensembl ID		ENSG00000102309	ENSG00000100325
Uniprot IDs		Q9Y237	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		1EQ3 1FJD 3UI4 3UI5 3UI6	2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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