SPOP and ILF3

Number of citations of the paper that reports this interaction (PubMedID 31772275)
8

Data Source:
BioGRID (enzymatic study)

		SPOP	ILF3
Description		speckle type BTB/POZ protein	interleukin enhancer binding factor 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Cul3-RING Ubiquitin Ligase Complex	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Protein Polyubiquitination Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Ischemic stroke ( 29531354) Obesity-related traits ( 23251661) Psoriasis ( 25903422 25574825 23143594) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Stroke ( 29531354) Systemic lupus erythematosus ( 28714469)
Interacting Genes		68 interacting genes: AEN AMOTL2 AR ARIH1 BRD2 BRD3 BRMS1 CACUL1 CBX4 CCNE1 CDK4 CHAF1A CHD3 CREB5 CTDSPL2 CUL3 DAXX DDIT3 DHX15 DPPA2 EGLN2 ERF ERG FAF1 GATAD2A GCC1 GCC2 GIT2 GLI2 GMEB1 HCST HMGCS1 ILF3 INF2 IRF1 KPNA5 LRCH4 MACROH2A1 MRE11 MYD88 NANOG NCOA3 NUDCD3 PDX1 PIAS1 PIAS3 RANBP9 RBFOX2 RBPJ RPRD2 RTN3 RXRB SETD2 SRRM1 SUMO1 TCOF1 TOPORS TRAF1 TRAF6 UBE2D1 UBE2D2 UBE2E3 UBE2I VPS9D1-AS1 YWHAG ZBTB16 ZCCHC12 ZMYND8	40 interacting genes: DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MAPK1 MDFI NDRG1 OGT PLSCR1 PPP1R12A PRMT1 PRMT5 PTEN RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC SPOP TRIM55 TRIM63 TRIP6 UBC VPS37C XAB2 XPO5 ZNF346 ZNF830
Entrez ID		8405	3609
HPRD ID		16004	04420
Ensembl ID		ENSG00000121067	ENSG00000129351
Uniprot IDs		O43791	A0A024R7C7 Q12906
PDB IDs		2CR2 3HQH 3HQI 3HQL 3HQM 3HSV 3HTM 3HU6 3IVB 3IVQ 3IVV 4EOZ 4HS2 4J8Z 4O1V 6F8F 6F8G 6I41 6I5P 6I68 6I7A 7D3D	2L33 3P1X
Enriched GO Terms of Interacting Partners?
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