CA8 and GGA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		CA8	GGA2
Description		carbonic anhydrase 8	golgi associated, gamma adaptin ear containing, ARF binding protein 2
Image
GO Annotations	Cellular Component	Cytoplasm	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport
Pathways			TBC/RABGAPs Amyloid fiber formation
Drugs		Zonisamide
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3	36 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 MEMO1 PIN1 RABEP1 RABGEF1 RNF11 RTN4IP1 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18
Entrez ID		767	23062
HPRD ID		00266	09347
Ensembl ID		ENSG00000178538	ENSG00000103365
Uniprot IDs		P35219	Q9UJY4
PDB IDs		2W2J	1MHQ
Enriched GO Terms of Interacting Partners?
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