GGA2 and VPS18

Number of citations of the paper that reports this interaction (PubMedID 16996030)
15

Data Source:
BioGRID (pull down, affinity chromatography technology)

		GGA2	VPS18
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 2	VPS18 core subunit of CORVET and HOPS complexes
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin-coated Vesicle Early Endosome Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Actin Filament AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding	Actin Binding Protein Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Intracellular Protein Transport Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Lysosome Organization Endosome To Lysosome Transport Protein Ubiquitination Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Viral Entry Into Host Cell Organelle Fusion Regulation Of Synaptic Vesicle Exocytosis
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS			Hemoglobin ( 32888494) Malaria ( 31844061) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		36 interacting genes: ADRA2B AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC FBXO7 GGA1 GGA3 GOLGA2 HGS HTT IGF2R LRP3 M6PR MAP3K1 MEMO1 PIN1 RABEP1 RABGEF1 RNF11 RTN4IP1 SORL1 SORT1 SPG21 STAB1 SYNRG TOLLIP TRIM23 VPS18	22 interacting genes: AKTIP CLCN3 COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B RAB7A RILP SHANK3 STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		23062	57617
HPRD ID		09347	09776
Ensembl ID		ENSG00000103365	ENSG00000104142
Uniprot IDs		Q9UJY4	A0A024R9R3 Q9P253
PDB IDs		1MHQ
Enriched GO Terms of Interacting Partners?
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