UPK2 and AMIGO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UPK2	AMIGO1
Description		uroplakin 2	adhesion molecule with Ig like domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Apical Plasma Membrane Extracellular Exosome	Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket
	Molecular Function	Protein Binding	Protein Binding Potassium Channel Regulator Activity
	Biological Process	Multicellular Organism Development Epithelial Cell Differentiation	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		33 interacting genes: ADGRG3 AMIGO1 ASGR2 ATP6AP2 BSCL2 BTNL9 C3orf52 CD74 CLDN7 CLEC17A CLEC7A FCGR1A FCGR2A FCGRT FNDC9 GPA33 HPN ITM2C KASH5 KIR2DL3 KIR3DL3 LIME1 PLP1 RNF170 SLC22A23 SMAGP STOML3 TMEM106C TMPRSS2 TNFSF11 TNFSF14 UPK1A ZNRF4	35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2
Entrez ID		7379	57463
HPRD ID		10295	11129
Ensembl ID		ENSG00000110375	ENSG00000181754
Uniprot IDs		O00526	Q86WK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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