UPK2 and ATP6AP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UPK2	ATP6AP2
Description		uroplakin 2	ATPase H+ transporting accessory protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Apical Plasma Membrane Extracellular Exosome	Autophagosome Membrane Lysosome Lysosomal Membrane Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Axon Dendritic Spine Membrane Cell Body Postsynaptic Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Multicellular Organism Development Epithelial Cell Differentiation	Angiotensin Maturation Lysosomal Lumen Acidification Central Nervous System Maturation Rostrocaudal Neural Tube Patterning Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta1 Production Regulation Of MAPK Cascade Eye Pigmentation Head Morphogenesis Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Metabolism of Angiotensinogen to Angiotensins Neutrophil degranulation
Drugs
Diseases
GWAS		Asthma ( 31959851)	Metabolite levels ( 23823483)
Interacting Genes		33 interacting genes: ADGRG3 AMIGO1 ASGR2 ATP6AP2 BSCL2 BTNL9 C3orf52 CD74 CLDN7 CLEC17A CLEC7A FCGR1A FCGR2A FCGRT FNDC9 GPA33 HPN ITM2C KASH5 KIR2DL3 KIR3DL3 LIME1 PLP1 RNF170 SLC22A23 SMAGP STOML3 TMEM106C TMPRSS2 TNFSF11 TNFSF14 UPK1A ZNRF4	21 interacting genes: ADRA1A AGT BBS1 CD72 CREB3 GLP1R HTR2C NKG7 NSG1 PMP22 PTTG1IP REN RPGR SEC22A TIMMDC1 TMEM203 TMEM97 UPK2 VAMP5 VKORC1 ZBTB16
Entrez ID		7379	10159
HPRD ID		10295	06454
Ensembl ID		ENSG00000110375	ENSG00000182220
Uniprot IDs		O00526	O75787
PDB IDs			3LBS 3LC8 6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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