AMIGO1 and HHATL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AMIGO1	HHATL
Description		adhesion molecule with Ig like domain 1	hedgehog acyltransferase like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Potassium Channel Regulator Activity	Protein Binding Acyltransferase Activity
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate	Negative Regulation Of N-terminal Protein Palmitoylation
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2	20 interacting genes: ADRA1A AGTR1 AMIGO1 BDKRB1 C4orf3 CACNA1A CISD2 CPLX4 CXCL16 ERGIC3 FAM209A FKBP7 FNDC9 GPR152 GPX8 MILR1 MUC1 PVR SUSD3 TMX2
Entrez ID		57463	57467
HPRD ID		11129	12166
Ensembl ID		ENSG00000181754	ENSG00000010282
Uniprot IDs		Q86WK6	A0A024R2R3 Q5QTR4 Q9HCP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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