AMIGO1 and AMIGO2

Number of citations of the paper that reports this interaction (PubMedID 12629050)
54

Data Source:
HPRD (in vitro, in vivo)

		AMIGO1	AMIGO2
Description		adhesion molecule with Ig like domain 1	adhesion molecule with Ig like domain 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Dendrite Neuronal Cell Body Membrane Perikaryon Pericellular Basket	Nucleus Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Potassium Channel Regulator Activity	Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Voltage-gated Potassium Channel Activity Cellular Response To L-glutamate	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Brain Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Synapse Assembly
Pathways			RAC1 GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)	Blood protein levels ( 30072576)
Interacting Genes		35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2	4 interacting genes: AMIGO1 AMIGO3 CACNA1A TMED8
Entrez ID		57463	347902
HPRD ID		11129	16483
Ensembl ID		ENSG00000181754	ENSG00000139211
Uniprot IDs		Q86WK6	A0A024R127 Q86SJ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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