TIAL1 and SNRPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIAL1	SNRPA
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	small nuclear ribonucleoprotein polypeptide A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Nucleoplasm Spliceosomal Complex U1 SnRNP
	Molecular Function	DNA Binding RNA Binding MRNA 3'-UTR Binding MRNA 3'-UTR AU-rich Region Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Germ Cell Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Posttranscriptional Gene Silencing Stem Cell Division Positive Regulation Of Hippo Signaling Positive Regulation Of Gene Silencing By MiRNA	MRNA Splicing, Via Spliceosome
Pathways		FGFR2 alternative splicing	mRNA Splicing - Major Pathway
Drugs			Malonic acid
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)	Blood protein levels ( 28240269) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	54 interacting genes: CDKN2A CHTOP CIRBP DAPK1 DAZAP1 DDIT4L DDX39B ENOX2 EP300 FBXO7 FUBP1 GABPB1 GIGYF1 HNRNPK IL7R LENG8 LHX4 LNX1 MBNL2 METTL13 MRPL15 MTUS2 NDUFAF3 OTX2 PAPOLA PCBP1 PCBP2 PCBP3 PTBP1 PTBP2 QKI RASAL3 RBM11 RBM3 RBM42 RBM4B RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 SDCBP SFPQ SMAD5 SNRPA1 TIAL1 TLE5 TNFAIP8L1 TRIM27 TRIR U2AF2 UBC WBP4 ZCCHC13
Entrez ID		7073	6626
HPRD ID		04563	01658
Ensembl ID		ENSG00000151923	ENSG00000077312
Uniprot IDs		Q01085 Q49AS9	P09012
PDB IDs		1X4G 2CQI 2DH7	1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6LAS 6LAU 6LAX 6LAZ 6QX9 6SQN 6SQQ 6SQT 6SQV 6SR7 6XH0 6XH1 6XH2 6XH3 7AEP 7B0Y 7D7V
Enriched GO Terms of Interacting Partners?
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