TIAL1 and RBPMS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIAL1	RBPMS2
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	RNA binding protein, mRNA processing factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Cytoplasm
	Molecular Function	DNA Binding RNA Binding MRNA 3'-UTR Binding MRNA 3'-UTR AU-rich Region Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Germ Cell Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Posttranscriptional Gene Silencing Stem Cell Division Positive Regulation Of Hippo Signaling Positive Regulation Of Gene Silencing By MiRNA	Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways		FGFR2 alternative splicing
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)	Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	68 interacting genes: AOC1 ARID5A BHLHE40 BOLL C10orf55 C19orf54 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA STRBP TENT5B TEX37 TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C
Entrez ID		7073	348093
HPRD ID		04563	18601
Ensembl ID		ENSG00000151923	ENSG00000166831
Uniprot IDs		Q01085 Q49AS9	Q6ZRY4
PDB IDs		1X4G 2CQI 2DH7	2M9K
Enriched GO Terms of Interacting Partners?
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