TIAL1 and BPIFA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TIAL1	BPIFA1
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	BPI fold containing family A member 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Extracellular Region Extracellular Space
	Molecular Function	DNA Binding RNA Binding MRNA 3'-UTR Binding MRNA 3'-UTR AU-rich Region Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Molecular_function Protein Binding Lipid Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Germ Cell Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Posttranscriptional Gene Silencing Stem Cell Division Positive Regulation Of Hippo Signaling Positive Regulation Of Gene Silencing By MiRNA	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport
Pathways		FGFR2 alternative splicing	Antimicrobial peptides
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765
Entrez ID		7073	51297
HPRD ID		04563	07594
Ensembl ID		ENSG00000151923	ENSG00000198183
Uniprot IDs		Q01085 Q49AS9	Q9NP55
PDB IDs		1X4G 2CQI 2DH7	4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?
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