SLPI and SMIM14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLPI	SMIM14
Description		secretory leukocyte peptidase inhibitor	small integral membrane protein 14
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding MRNA Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding	Protein Binding
	Biological Process	Immune Response Negative Regulation Of Endopeptidase Activity Antibacterial Humoral Response Negative Regulation Of Protein Binding Response To Lipopolysaccharide Modulation Of Process Of Other Organism Negative Regulation Of Viral Genome Replication Innate Immune Response	Blastocyst Hatching
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 30072576 28240269) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Malaria ( 31844061)	Triglyceride levels ( 32203549)
Interacting Genes		25 interacting genes: CALN1 CIB3 CTSB CTSL CTSS EFEMP1 ELANE FAM9B GRN HOXA1 KLK3 LAT MAPK8IP2 MICOS10-NBL1 MKRN3 NBL1 NTAQ1 PIH1D2 PLSCR1 PRSS2 SGTA SGTB SMIM14 UBQLN1 UBQLN2	5 interacting genes: FATE1 LSM4 SGTA SLPI TMEM42
Entrez ID		6590	201895
HPRD ID		00121	14129
Ensembl ID		ENSG00000124107	ENSG00000163683
Uniprot IDs		P03973	A0A024R9U4 Q96QK8
PDB IDs		2Z7F 4DOQ
Enriched GO Terms of Interacting Partners?
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