SELE and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 22970241)
23

Data Source:
BioGRID (pull down)

		SELE	LGALS3BP
Description		selectin E	galectin 3 binding protein
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Caveola Clathrin-coated Pit External Side Of Plasma Membrane Cortical Cytoskeleton Membrane Raft Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Membrane Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Sialic Acid Binding Phospholipase Binding Metal Ion Binding Oligosaccharide Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Leukocyte Migration Involved In Inflammatory Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Activation Of Phospholipase C Activity Calcium-mediated Signaling Actin Filament-based Process Response To Lipopolysaccharide Response To Cytokine Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukocyte Tethering Or Rolling Response To Interleukin-1 Positive Regulation Of Leukocyte Tethering Or Rolling	Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Cell surface interactions at the vascular wall	Platelet degranulation
Drugs		Carvedilol N-acetyl-alpha-neuraminic acid Endostatin
Diseases
GWAS		Blood protein levels ( 30072576) Inflammatory bowel disease ( 26192919) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494)	Blood protein levels ( 30072576)
Interacting Genes		15 interacting genes: ACTA2 ACTN2 CD44 FLNA GLG1 LGALS3BP PLCG1 PTK2 PTPN11 PXN SELL SELPLG SERPING1 TRIM54 VCL	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		6401	3959
HPRD ID		00566	02796
Ensembl ID		ENSG00000007908	ENSG00000108679
Uniprot IDs		P16581	A0A0S2Z3Y1 Q08380
PDB IDs		1ESL 1G1T 1KJA 4C16 4CSY 6EYI 6EYJ 6EYK	1BY2 6GFB
Enriched GO Terms of Interacting Partners?
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