CALCOCO1 and PCBD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		CALCOCO1	PCBD1
Description		calcium binding and coiled-coil domain 1	pterin-4 alpha-carbinolamine dehydratase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Coactivator Activity Sequence-specific DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	L-phenylalanine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated
Pathways			Phenylalanine metabolism
Drugs			L-erythro-7,8-dihydrobiopterin
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2	54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714
Entrez ID		57658	5092
HPRD ID		13868	00523
Ensembl ID		ENSG00000012822	ENSG00000166228
Uniprot IDs		A0A024RAZ1 Q9P1Z2	P61457
PDB IDs
Enriched GO Terms of Interacting Partners?
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