CALCOCO1 and TBC1D15

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CALCOCO1	TBC1D15
Description		calcium binding and coiled-coil domain 1	TBC1 domain family member 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Coactivator Activity Sequence-specific DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	GTPase Activator Activity Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)
Interacting Genes		37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2	9 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C TAX1BP1 UBC
Entrez ID		57658	64786
HPRD ID		13868	15470
Ensembl ID		ENSG00000012822	ENSG00000121749
Uniprot IDs		A0A024RAZ1 Q9P1Z2	A8K8E1 Q8TC07
PDB IDs
Enriched GO Terms of Interacting Partners?
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