GRAMD4 and TACC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GRAMD4	TACC2
Description		GRAM domain containing 4	transforming acidic coiled-coil containing protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane
	Molecular Function	Molecular_function Protein Binding	Nuclear Receptor Binding
	Biological Process	Apoptotic Process Negative Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development
Pathways
Drugs
Diseases
GWAS		Urate levels in obese individuals ( 25811787)	Chronic lymphocytic leukemia (time to first treatment) ( 33510140) Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)
Interacting Genes		14 interacting genes: APP C2CD6 CCDC146 EXOC8 FAM9B GADD45G MTMR9 NTAQ1 PKDREJ PLEKHF2 RBL2 SH2D4A SMARCD1 TACC2	18 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 FMR1 FXR1 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCA2 SMARCB1 TGM1 YEATS4
Entrez ID		23151	10579
HPRD ID		11107	05600
Ensembl ID		ENSG00000075240	ENSG00000138162
Uniprot IDs		Q6IC98	B2RWP4 B7ZMJ9 D6RAA5 O95359 Q4VXL4 Q4VXL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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