RHBDD2 and MRM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RHBDD2	MRM1
Description		rhomboid domain containing 2	mitochondrial rRNA methyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix
	Molecular Function	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding	RNA Binding Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response	RRNA 2'-O-methylation
Pathways			rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30	44 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CGGBP1 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 GSDMB ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1
Entrez ID		57414	79922
HPRD ID		11492	08656
Ensembl ID		ENSG00000005486	ENSG00000278619
Uniprot IDs		Q6NTF9	Q6IN84
PDB IDs
Enriched GO Terms of Interacting Partners?
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