RHBDD2 and USP30

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RHBDD2	USP30
Description		rhomboid domain containing 2	ubiquitin specific peptidase 30
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Cytosol Integral Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Deubiquitinase Activity
	Biological Process	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response	Autophagy Of Mitochondrion Pexophagy Ubiquitin-dependent Protein Catabolic Process Mitochondrial Fusion Protein Deubiquitination Protein K11-linked Deubiquitination Protein K6-linked Deubiquitination Negative Regulation Of Mitophagy
Pathways			Ub-specific processing proteases Pexophagy
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252)
Interacting Genes		58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30	4 interacting genes: PRKN RHBDD2 UBB UBC
Entrez ID		57414	84749
HPRD ID		11492	15633
Ensembl ID		ENSG00000005486	ENSG00000135093
Uniprot IDs		Q6NTF9	A0A024RBM3 B3KUS5 Q70CQ3
PDB IDs			5OHK 5OHN 5OHP
Enriched GO Terms of Interacting Partners?
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