MRM1 and VKORC1L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MRM1	VKORC1L1
Description		mitochondrial rRNA methyltransferase 1	vitamin K epoxide reductase complex subunit 1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding
	Biological Process	RRNA 2'-O-methylation	Peptidyl-glutamic Acid Carboxylation Cellular Response To Oxidative Stress Vitamin K Metabolic Process
Pathways		rRNA modification in the mitochondrion	Metabolism of vitamin K
Drugs			Menadione
Diseases
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)	Calcium levels ( 24068962) Corneal structure ( 23291589) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 30591961) Neutrophil count ( 32888494)
Interacting Genes		44 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CGGBP1 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 GSDMB ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	11 interacting genes: AQP6 CISD2 ERGIC3 GORAB GPX8 MRM1 MS4A3 MTIF3 PCYT1A PCYT1B TMEM80
Entrez ID		79922	154807
HPRD ID		08656	12312
Ensembl ID		ENSG00000278619	ENSG00000196715
Uniprot IDs		Q6IN84	A8K0F7 Q8N0U8
PDB IDs
Enriched GO Terms of Interacting Partners?
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