BCCIP and CAPZB

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BCCIP	CAPZB
Description		BRCA2 and CDKN1A interacting protein	capping actin protein of muscle Z-line subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Cytosol Cytoskeleton Brush Border F-actin Capping Protein Complex Postsynaptic Density Actin Cytoskeleton Membrane Sarcomere Lamellipodium Cortical Cytoskeleton Extracellular Exosome WASH Complex Sperm Connecting Piece Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	RNA Binding Protein Binding Kinase Regulator Activity	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization DNA Repair Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Cell Morphogenesis Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Lamellipodium Assembly Regulation Of Cell Morphogenesis Lamellipodium Assembly Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic RHOD GTPase cycle RHOF GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)
Interacting Genes		29 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CENPJ CSNK2B FCF1 GSK3A GSK3B H2BC15 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A TP53 YY1 ZNF138 ZNF19	9 interacting genes: BCCIP CDC42 HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL
Entrez ID		56647	832
HPRD ID		16542	11872
Ensembl ID		ENSG00000107949	ENSG00000077549
Uniprot IDs		Q9P287	A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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