BCCIP and PTPRM

Number of citations of the paper that reports this interaction (PubMedID 18773424)
6

Data Source:
BioGRID (pull down, enzymatic study, pull down)

		BCCIP	PTPRM
Description		BRCA2 and CDKN1A interacting protein	protein tyrosine phosphatase receptor type M
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Kinase Regulator Activity	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization DNA Repair Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Negative Regulation Of Endothelial Cell Proliferation Protein Dephosphorylation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Response To Xenobiotic Stimulus Negative Regulation Of Endothelial Cell Migration Retina Layer Formation Negative Regulation Of Angiogenesis Neuron Projection Development Retinal Ganglion Cell Axon Guidance Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Adult body size ( 32376654) Benign childhood epilepsy with centro-temporal spikes ( 32580138) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Dialysis-related mortality ( 21546767) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Glucose homeostasis traits ( 25524916) Hippocampal volume ( 29860282) Huntington's disease progression ( 28642124) Iris heterochromicity ( 30895295) Lateral ventricle temporal horn volume ( 31530798) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Recurrence of mild malaria attacks ( 31667592) Response to methotrexate in rheumatoid arthritis ( 24583629) Sitting height ratio ( 25865494)
Interacting Genes		29 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CENPJ CSNK2B FCF1 GSK3A GSK3B H2BC15 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A TP53 YY1 ZNF138 ZNF19	12 interacting genes: AKAP6 BCCIP CDH1 CTNNB1 CTNND1 IQGAP1 PCSK5 PPFIBP1 PTPRA PTPRK PTPRS RACK1
Entrez ID		56647	5797
HPRD ID		16542	01479
Ensembl ID		ENSG00000107949	ENSG00000173482
Uniprot IDs		Q9P287	P28827
PDB IDs			1RPM 2C9A 2V5Y
Enriched GO Terms of Interacting Partners?
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