BCCIP and ABCB1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		BCCIP	ABCB1
Description		BRCA2 and CDKN1A interacting protein	ATP binding cassette subfamily B member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Nucleoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Extracellular Exosome External Side Of Apical Plasma Membrane
	Molecular Function	RNA Binding Protein Binding Kinase Regulator Activity	Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity Efflux Transmembrane Transporter Activity Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Carboxylic Acid Transmembrane Transporter Activity Phosphatidylcholine Floppase Activity Phosphatidylethanolamine Flippase Activity Ceramide Floppase Activity Floppase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization DNA Repair Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	G2/M Transition Of Mitotic Cell Cycle Response To Xenobiotic Stimulus Phospholipid Translocation Terpenoid Transport Regulation Of Response To Osmotic Stress Transmembrane Transport Transepithelial Transport Stem Cell Proliferation Ceramide Translocation Export Across Plasma Membrane Transport Across Blood-brain Barrier Positive Regulation Of Anion Channel Activity Carboxylic Acid Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Xenobiotic Transport Across Blood-brain Barrier Regulation Of Chloride Transport
Pathways			Abacavir transmembrane transport ABC-family proteins mediated transport
Drugs			ATP Medroxyprogesterone acetate Roxithromycin Fentanyl Voacamine Elacridar Tesmilifene FM-VP4 Zosuquidar Tariquidar Miltefosine Tocofersolan Hycanthone Concanamycin A Dexverapamil Emopamil Lomerizine Tetrandrine Dofequidar Dexniguldipine ONT-093 HM-30181 Desmethylsertraline Reversin 121
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Bone mineral density (spine) and age at menarche ( 26312577) Cerebral microbleeds ( 32913026) Gallbladder cancer ( 28274756) Liver enzyme levels (alanine transaminase) ( 33972514) Neurological blood protein biomarker levels ( 31320639) Persistent chemotherapy-induced alopecia in breast cancer ( 32756886)
Interacting Genes		29 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CENPJ CSNK2B FCF1 GSK3A GSK3B H2BC15 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A TP53 YY1 ZNF138 ZNF19	11 interacting genes: BCCIP CAV1 CD4 HAX1 LNX1 MAPKAP1 MAPRE1 NEDD4 PIM1 PSMB8 RNF2
Entrez ID		56647	5243
HPRD ID		16542	01370
Ensembl ID		ENSG00000107949	ENSG00000085563
Uniprot IDs		Q9P287	A4D1D2 P08183
PDB IDs			6C0V 6FN1 6FN4 6QEX 7A65 7A69 7A6C 7A6E 7A6F
Enriched GO Terms of Interacting Partners?
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