BCCIP and CENPJ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BCCIP	CENPJ
Description		BRCA2 and CDKN1A interacting protein	centromere protein J
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Centriole Cytosol Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Microtubule Plasma Membrane Gamma-tubulin Small Complex
	Molecular Function	RNA Binding Protein Binding Kinase Regulator Activity	Transcription Coactivator Activity Protein Binding Tubulin Binding Protein Kinase Binding Protein Domain Specific Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization DNA Repair Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Microtubule Nucleation Centriole Replication Astral Microtubule Nucleation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Centriole Replication Microtubule Polymerization Cell Division Cilium Assembly Centriole Elongation Positive Regulation Of Centriole Elongation Positive Regulation Of Establishment Of Protein Localization
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		29 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CENPJ CSNK2B FCF1 GSK3A GSK3B H2BC15 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A TP53 YY1 ZNF138 ZNF19	16 interacting genes: ATN1 BCCIP CIC CREBBP EPB41 FBXO7 GFI1B LAG3 LYST MTDH SHANK3 STAT5A STAT5B TUBG1 YWHAG YWHAZ
Entrez ID		56647	55835
HPRD ID		16542	09876
Ensembl ID		ENSG00000107949	ENSG00000151849
Uniprot IDs		Q9P287	A8K8P1 F6VUX8 Q9HC77
PDB IDs			5EIB 5ITZ
Enriched GO Terms of Interacting Partners?
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