HAS3 and SYNGR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HAS3	SYNGR1
Description		hyaluronan synthase 3	synaptogyrin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Hyaluranon Cable	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome
	Molecular Function	Protein Binding Identical Protein Binding Hyaluronan Synthase Activity	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Hyaluronan Biosynthetic Process Extracellular Polysaccharide Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Extracellular Matrix Assembly Positive Regulation Of Hyaluranon Cable Assembly	Protein Targeting Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor
Pathways		Hyaluronan biosynthesis and export	Neutrophil degranulation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18821565) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653)	Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 32723749 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Systemic lupus erythematosus ( 33272962) Ulcerative colitis ( 28067908) vWF levels ( 30586737)
Interacting Genes		7 interacting genes: APOL3 C14orf180 CCR1 CMTM7 LHFPL5 PLP1 SYNGR1	31 interacting genes: ADORA2A AQP6 CACNA1I CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A
Entrez ID		3038	9145
HPRD ID		03889	06800
Ensembl ID		ENSG00000103044	ENSG00000100321
Uniprot IDs		O00219 Q96RV2	O43759
PDB IDs
Enriched GO Terms of Interacting Partners?
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