HAS3 and APOL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HAS3	APOL3
Description		hyaluronan synthase 3	apolipoprotein L3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Hyaluranon Cable	Extracellular Region Cytoplasm Membrane
	Molecular Function	Protein Binding Identical Protein Binding Hyaluronan Synthase Activity	Lipid Transporter Activity Lipid Binding
	Biological Process	Carbohydrate Metabolic Process Hyaluronan Biosynthetic Process Extracellular Polysaccharide Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Extracellular Matrix Assembly Positive Regulation Of Hyaluranon Cable Assembly	Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Hyaluronan biosynthesis and export
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18821565) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Total intracranial volume ( 31530798)
Interacting Genes		7 interacting genes: APOL3 C14orf180 CCR1 CMTM7 LHFPL5 PLP1 SYNGR1	28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D
Entrez ID		3038	80833
HPRD ID		03889	06264
Ensembl ID		ENSG00000103044	ENSG00000128284
Uniprot IDs		O00219 Q96RV2	A0A024R1G6 O95236
PDB IDs
Enriched GO Terms of Interacting Partners?
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