SYNGR1 and CACNA1I

		SYNGR1	CACNA1I
Description		synaptogyrin 1	calcium voltage-gated channel subunit alpha1 I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome	Voltage-gated Sodium Channel Complex Voltage-gated Calcium Channel Complex Neuron Projection
	Molecular Function	Protein Binding	Voltage-gated Calcium Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity
	Biological Process	Protein Targeting Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor	Signal Transduction Neuronal Action Potential Flagellated Sperm Motility Sleep Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways		Neutrophil degranulation	NCAM1 interactions
Drugs			Ergocalciferol Enflurane Amlodipine Spironolactone Cinnarizine Paramethadione Zonisamide Nifedipine Amiodarone Mibefradil Flunarizine Nylidrin Cannabidiol Trimebutine Benidipine Efonidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 32723749 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Systemic lupus erythematosus ( 33272962) Ulcerative colitis ( 28067908) vWF levels ( 30586737)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Hodgkin's lymphoma ( 34216518) Household income (MTAG) ( 31844048) IgG glycosylation ( 23382691) Intelligence (MTAG) ( 29326435) Negative urgency ( 30718321) Refractive error ( 32231278) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Schizophrenia ( 28991256 22883433 29483656 30285260)
Interacting Genes		31 interacting genes: ADORA2A AQP6 CACNA1I CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A	11 interacting genes: APOBEC1 APOL1 DNAL4 GTPBP1 HMGXB4 JOSD1 PICK1 PLA2G6 SYNGR1 TST VPS28
Entrez ID		9145	8911
HPRD ID		06800	10500
Ensembl ID		ENSG00000100321	ENSG00000100346
Uniprot IDs		O43759	Q9P0X4
PDB IDs
Enriched GO Terms of Interacting Partners?
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