OLA1 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OLA1	ASCC2
Description		Obg like ATPase 1	activating signal cointegrator 1 complex subunit 2
Image
GO Annotations	Cellular Component	Extracellular Region Nucleolus Cytoplasm Centrosome Cytosol Membrane Platelet Alpha Granule Lumen Extracellular Exosome	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	Protein Binding ATP Binding GTP Binding Hydrolase Activity ATP Hydrolysis Activity Ribosome Binding Ribosomal Large Subunit Binding Cadherin Binding Metal Ion Binding	Protein Binding Ubiquitin Binding
	Biological Process	ATP Metabolic Process	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Platelet degranulation	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Hand grip strength ( 29691431) Reaction time ( 29844566) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		7 interacting genes: ASCC2 CDC42 HMGA1 LINC01554 OGT PRMT5 RACK1	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		29789	84164
HPRD ID		15194	16515
Ensembl ID		ENSG00000138430	ENSG00000100325
Uniprot IDs		Q9NTK5	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		2OHF	2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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