CHMP2A and KERA

		CHMP2A	KERA
Description		charged multivesicular body protein 2A	keratocan
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding	Molecular_function
	Biological Process	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly	Visual Perception Response To Stimulus Cornea Development In Camera-type Eye
Pathways		Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494)	Pre-treatment viral load in HIV-1 infection ( 31219150) Pulmonary function (smoking interaction) ( 23284291) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		21 interacting genes: CHD3 CHMP3 CYP4F2 DOCK8 E2F4 EIF2B5 ITGA5 KERA MAPKAPK3 MITD1 NCOA1 NOL4 SLC25A1 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B ZNF32	2 interacting genes: CHMP2A UNG
Entrez ID		27243	11081
HPRD ID		12520	04477
Ensembl ID		ENSG00000130724	ENSG00000139330
Uniprot IDs		A0A024R4S0 O43633	O60938
PDB IDs
Enriched GO Terms of Interacting Partners?
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