CHMP2A and MITD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid, in vivo)

		CHMP2A	MITD1
Description		charged multivesicular body protein 2A	microtubule interacting and trafficking domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome	Extrinsic Component Of Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly	Mitotic Cytokinesis Negative Regulation Of Protein Binding Viral Budding Via Host ESCRT Complex Midbody Abscission Multivesicular Body Sorting Pathway
Pathways		Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494)	Bipolar disorder ( 21926972)
Interacting Genes		21 interacting genes: CHD3 CHMP3 CYP4F2 DOCK8 E2F4 EIF2B5 ITGA5 KERA MAPKAPK3 MITD1 NCOA1 NOL4 SLC25A1 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B ZNF32	15 interacting genes: ATF7 CARD10 CHMP1A CHMP1B CHMP2A CHMP5 GPHN KANK2 MCPH1 NTAQ1 RTN3 TRIM14 TTC33 ZFYVE19 ZNF655
Entrez ID		27243	129531
HPRD ID		12520	14044
Ensembl ID		ENSG00000130724	ENSG00000158411
Uniprot IDs		A0A024R4S0 O43633	Q8WV92
PDB IDs			2YMB 4A5X 4A5Z
Enriched GO Terms of Interacting Partners?
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