CHMP2A and STAMBP

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		CHMP2A	STAMBP
Description		charged multivesicular body protein 2A	STAM binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding	Thiol-dependent Deubiquitinase Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity
	Biological Process	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Metalloprotease DUBs
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494)	Anti-saccade response ( 29064472) Bell's palsy ( 33602968) Blood metabolite levels ( 26401656) Serum metabolite levels ( 33031748 23093944)
Interacting Genes		21 interacting genes: CHD3 CHMP3 CYP4F2 DOCK8 E2F4 EIF2B5 ITGA5 KERA MAPKAPK3 MITD1 NCOA1 NOL4 SLC25A1 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B ZNF32	46 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S ULK1 USP21 USP28
Entrez ID		27243	10617
HPRD ID		12520	05877
Ensembl ID		ENSG00000130724	ENSG00000124356
Uniprot IDs		A0A024R4S0 O43633	A0A140VK54 O95630
PDB IDs			2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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