KERA and UNG

		KERA	UNG
Description		keratocan	uracil DNA glycosylase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Molecular_function	Damaged DNA Binding Uracil DNA N-glycosylase Activity Protein Binding Ribosomal Small Subunit Binding
	Biological Process	Visual Perception Response To Stimulus Cornea Development In Camera-type Eye	DNA Repair Base-excision Repair Somatic Hypermutation Of Immunoglobulin Genes Negative Regulation Of Apoptotic Process Depyrimidination Isotype Switching Base-excision Repair, AP Site Formation Via Deaminated Base Removal
Pathways		Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Drugs			4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150) Pulmonary function (smoking interaction) ( 23284291) Systolic blood pressure (alcohol consumption interaction) ( 24376456)	Feeling miserable ( 29500382) Feeling worry ( 29500382) Neurociticism ( 29500382) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		2 interacting genes: CHMP2A UNG	15 interacting genes: APP ATP2A2 CAPN11 CCDC33 CRY1 DAO FTH1 KERA P2RY6 PCNA PRDM4 RPA2 RPS20 SEZ6L2 SLC17A7
Entrez ID		11081	7374
HPRD ID		04477	01881
Ensembl ID		ENSG00000139330	ENSG00000076248
Uniprot IDs		O60938	E5KTA5 E5KTA6 P13051
PDB IDs			1AKZ 1DPU 1EMH 1EMJ 1Q3F 1SSP 1UGH 1YUO 2HXM 2OXM 2OYT 2SSP 3FCF 3FCI 3FCK 3FCL 3TKB 4SKN 5AYR 5JK7 6VBA
Enriched GO Terms of Interacting Partners?
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