B3GAT1 and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		B3GAT1	SH3GL1
Description		beta-1,3-glucuronyltransferase 1	SH3 domain containing GRB2 like 1, endophilin A2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Podosome Cytoplasm Cytosol Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Protein Binding UDP-galactose:beta-N-acetylglucosamine Beta-1,3-galactosyltransferase Activity Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Metal Ion Binding	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Cadherin Binding GTPase Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Chondroitin Sulfate Proteoglycan Biosynthetic Process Cellular Response To Hypoxia	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis	EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs		D-tartaric acid Uridine-5'-Diphosphate
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) N-glycan levels ( 21908519) Neonatal white matter microstructure ( 33009551) Prostate cancer ( 29892016) Schizophrenia ( 33169155) Serum alkaline phosphatase levels ( 33547301) Verbal declarative memory ( 25648963)	Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		3 interacting genes: CMTM7 HLA-DMA SH3GL1	37 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PRR5-ARHGAP8 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 STK11 SYNJ1 VPS37C YWHAZ
Entrez ID		27087	6455
HPRD ID		06969	03462
Ensembl ID		ENSG00000109956	ENSG00000141985
Uniprot IDs		Q9P2W7	Q6FGM0 Q99961
PDB IDs		1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?
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