B3GAT1 and CMTM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		B3GAT1	CMTM7
Description		beta-1,3-glucuronyltransferase 1	CKLF like MARVEL transmembrane domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding UDP-galactose:beta-N-acetylglucosamine Beta-1,3-galactosyltransferase Activity Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Metal Ion Binding	Cytokine Activity Protein Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Chondroitin Sulfate Proteoglycan Biosynthetic Process Cellular Response To Hypoxia	B-1a B Cell Differentiation Chemotaxis Signal Transduction
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis
Drugs		D-tartaric acid Uridine-5'-Diphosphate
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) N-glycan levels ( 21908519) Neonatal white matter microstructure ( 33009551) Prostate cancer ( 29892016) Schizophrenia ( 33169155) Serum alkaline phosphatase levels ( 33547301) Verbal declarative memory ( 25648963)	Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		3 interacting genes: CMTM7 HLA-DMA SH3GL1	48 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 DYNC1LI1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17
Entrez ID		27087	112616
HPRD ID		06969	06988
Ensembl ID		ENSG00000109956	ENSG00000153551
Uniprot IDs		Q9P2W7	F8WDZ3 Q96FZ5
PDB IDs		1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?
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