PLA2G15 and RNF7

Number of citations of the paper that reports this interaction (PubMedID 10230407)
172

Data Source:
HPRD (two hybrid, in vivo)

		PLA2G15	RNF7
Description		phospholipase A2 group XV	ring finger protein 7
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Lysophospholipase Activity Phospholipase A2 Activity Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phosphatidyl Phospholipase B Activity	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Response To Redox State
Pathways		Hydrolysis of LPC	Neddylation Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum metabolite levels ( 33031748) Waist circumference adjusted for body mass index ( 34021172)	Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		11 interacting genes: COG4 DDX19B EDC4 IMMT LRRC29 PLEKHG4 RNF7 SF3B3 TMEM208 VPS4A WWP2	41 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2L3 UBE2M UBE2Q1
Entrez ID		23659	9616
HPRD ID		07128	04840
Ensembl ID		ENSG00000103066	ENSG00000114125
Uniprot IDs		Q8NCC3	Q9UBF6
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	2ECL
Enriched GO Terms of Interacting Partners?
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