PLA2G15 and VPS4A

		PLA2G15	VPS4A
Description		phospholipase A2 group XV	vacuolar protein sorting 4 homolog A
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Spindle Pole Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Cytosol Plasma Membrane Endosome Membrane Midbody Late Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Flemming Body
	Molecular Function	Lysophospholipase Activity Phospholipase A2 Activity Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phosphatidyl Phospholipase B Activity	Protein Binding ATP Binding Protein C-terminus Binding ATP Hydrolysis Activity Protein Domain Specific Binding Protein-containing Complex Binding Protein Disaggregase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	Actomyosin Contractile Ring Contraction Protein Targeting To Lysosome Vesicle Budding From Membrane Nucleus Organization Nuclear Envelope Organization Vacuole Organization Mitotic Metaphase Plate Congression Mitotic Nuclear Membrane Reassembly Abscission Vesicle-mediated Transport Endosomal Transport Macroautophagy Nuclear Membrane Reassembly Intracellular Cholesterol Transport Negative Regulation Of Cytokinesis Regulation Of Protein Localization Endosomal Vesicle Fusion Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Cell Division Cytoskeleton-dependent Cytokinesis Late Endosomal Microautophagy Midbody Abscission Vesicle Uncoating Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Release From Host Cell Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Exosomal Secretion Positive Regulation Of Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Life Cycle ESCRT Complex Disassembly ESCRT III Complex Disassembly
Pathways		Hydrolysis of LPC	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum metabolite levels ( 33031748) Waist circumference adjusted for body mass index ( 34021172)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol ( 30275531) Logical memory (delayed recall) in normal cognition ( 29274321) Total cholesterol levels in HDL ( 29084231)
Interacting Genes		11 interacting genes: COG4 DDX19B EDC4 IMMT LRRC29 PLEKHG4 RNF7 SF3B3 TMEM208 VPS4A WWP2	12 interacting genes: CHMP1A CHMP1B CHMP2A CHMP4A CHMP4B CHMP4C CLIC3 NPC1 OGT PLA2G15 RND2 VPS4B
Entrez ID		23659	27183
HPRD ID		07128	11676
Ensembl ID		ENSG00000103066	ENSG00000132612
Uniprot IDs		Q8NCC3	A0A024R705 Q9UN37
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	1YXR 2JQ9 2K3W
Enriched GO Terms of Interacting Partners?
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