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RNF7

Description ring finger protein 7
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Cullin-RING Ubiquitin Ligase Complex
  • Cul5-RING Ubiquitin Ligase Complex
Molecular Function
  • Copper Ion Binding
  • Protein Binding
  • Zinc Ion Binding
  • NEDD8 Transferase Activity
  • Ubiquitin Protein Ligase Activity
  • NEDD8 Ligase Activity
  • Cullin Family Protein Binding
Biological Process
  • Ubiquitin-dependent Protein Catabolic Process
  • Protein Ubiquitination
  • Post-translational Protein Modification
  • Protein Neddylation
  • Response To Redox State
Pathways
  • Neddylation
  • Inactivation of CSF3 (G-CSF) signaling
  • Inactivation of CSF3 (G-CSF) signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Hepatitis C induced liver fibrosis ( 22841784)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes 41 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2L3 UBE2M UBE2Q1
Entrez ID 9616
HPRD ID 04840
Ensembl ID ENSG00000114125
Uniprot IDs Q9UBF6
PDB IDs 2ECL
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025