RNF7 and APOBEC3F

Number of citations of the paper that reports this interaction (PubMedID 31253590)
13

Data Source:
BioGRID (enzymatic study)

		RNF7	APOBEC3F
Description		ring finger protein 7	apolipoprotein B mRNA editing enzyme catalytic subunit 3F
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex	P-body Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex Ribonucleoprotein Complex
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Deoxycytidine Deaminase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Response To Redox State	Positive Regulation Of Defense Response To Virus By Host Cytidine Deamination Negative Regulation Of Transposition Base Conversion Or Substitution Editing Cytidine To Uridine Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Viral Process Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways		Neddylation Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		41 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2L3 UBE2M UBE2Q1	6 interacting genes: ACD APOBEC3G ARIH2 RNF7 TINF2 TYK2
Entrez ID		9616	200316
HPRD ID		04840	16415
Ensembl ID		ENSG00000114125	ENSG00000128394
Uniprot IDs		Q9UBF6	Q8IUX4
PDB IDs		2ECL	3WUS 4IOU 4J4J 5HX4 5HX5 5W2M 6NIL
Enriched GO Terms of Interacting Partners?
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