DCUN1D4 and CUL4B

Number of citations of the paper that reports this interaction (PubMedID 23201271)
45

Data Source:
BioGRID (enzymatic study)

		DCUN1D4	CUL4B
Description		defective in cullin neddylation 1 domain containing 4	cullin 4B
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus	Nucleoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Exosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding	Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Neddylation	G1/S Transition Of Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Proteasomal Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Development Histone H2A Monoubiquitination Ribosome Biogenesis UV-damage Excision Repair
Pathways		Neddylation	Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Familial squamous cell lung carcinoma ( 29924316) Height ( 28552196)
Interacting Genes		8 interacting genes: CAND1 CEP135 CUL2 CUL3 CUL4A CUL4B UBE2M VAV2	55 interacting genes: AHR AMBRA1 APP AR BRWD1 BRWD3 CAND1 COMMD1 COP1 COPS2 COPS5 CRBN CUL4A DCAF10 DCAF11 DCAF12 DCAF15 DCAF16 DCAF17 DCAF4 DCAF5 DCAF6 DCUN1D1 DCUN1D4 DDA1 DDB1 DDB2 DET1 DNMT3B DTL ERCC8 ESR1 GLMN HUWE1 KPNA2 KPNA4 KPNB1 NEDD8 PHIP PLS3 PRDX3 PTEN PWP1 RBX1 RNF7 SALL2 SIN3A SRC ST7 TBL3 TRPC4AP UBC UBE2D3 WDTC1 ZMAT4
Entrez ID		23142	8450
HPRD ID		13791	02251
Ensembl ID		ENSG00000109184	ENSG00000158290
Uniprot IDs		B4DH26 Q92564	K4DI93 Q13620
PDB IDs		5V89	2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?
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